Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial.
Identifieur interne : 002E42 ( Main/Exploration ); précédent : 002E41; suivant : 002E43Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial.
Auteurs : Alistair Nichol [Irlande (pays)] ; Craig French [Australie] ; Lorraine Little [Australie] ; Samir Haddad [Arabie saoudite] ; Jeffrey Presneill [Australie] ; Yaseen Arabi [Arabie saoudite] ; Michael Bailey [Australie] ; D James Cooper [Australie] ; Jacques Duranteau [France] ; Olivier Huet [France] ; Anne Mak [Australie] ; Colin Mcarthur [Nouvelle-Zélande] ; Ville Pettil [Finlande] ; Markus Skrifvars [Finlande] ; Shirley Vallance [Australie] ; Dinesh Varma [Australie] ; Judy Wills [Australie] ; Rinaldo Bellomo [Australie]Source :
- Lancet (London, England) [ 1474-547X ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Arabie saoudite (épidémiologie), Australie (épidémiologie), Europe (épidémiologie), Femelle, Humains, Incidence, Jeune adulte, Lésions encéphaliques (mortalité), Lésions encéphaliques (traitement médicamenteux), Mâle, Méthode en double aveugle, Nouvelle-Zélande (épidémiologie), Résultat thérapeutique, Thrombose veineuse (épidémiologie), Échelle de suivi de Glasgow, Érythropoïétine (usage thérapeutique).
- MESH :
- mortalité : Lésions encéphaliques.
- traitement médicamenteux : Lésions encéphaliques.
- usage thérapeutique : Érythropoïétine.
- épidémiologie : Arabie saoudite, Australie, Europe, Nouvelle-Zélande, Thrombose veineuse.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Incidence, Jeune adulte, Mâle, Méthode en double aveugle, Résultat thérapeutique, Échelle de suivi de Glasgow.
- Wicri :
- geographic : Australie, Nouvelle-Zélande, Arabie saoudite.
English descriptors
- KwdEn :
- Adult, Australia (epidemiology), Brain Injuries (drug therapy), Brain Injuries (mortality), Double-Blind Method, Erythropoietin (therapeutic use), Europe (epidemiology), Female, Glasgow Outcome Scale, Humans, Incidence, Male, Middle Aged, New Zealand (epidemiology), Saudi Arabia (epidemiology), Treatment Outcome, Venous Thrombosis (epidemiology), Young Adult.
- MESH :
- chemical , therapeutic use : Erythropoietin.
- geographic , epidemiology : Australia, Europe, New Zealand, Saudi Arabia.
- drug therapy : Brain Injuries.
- epidemiology : Venous Thrombosis.
- mortality : Brain Injuries.
- Adult, Double-Blind Method, Female, Glasgow Outcome Scale, Humans, Incidence, Male, Middle Aged, Treatment Outcome, Young Adult.
Abstract
Erythropoietin might have neurocytoprotective effects. In this trial, we studied its effect on neurological recovery, mortality, and venous thrombotic events in patients with traumatic brain injury.
DOI: 10.1016/S0140-6736(15)00386-4
PubMed: 26452709
Affiliations:
- Arabie saoudite, Australie, Finlande, France, Irlande (pays), Nouvelle-Zélande
- Région Bretagne, Victoria (État), Île-de-France
- Brest, Melbourne, Paris
- Université de Melbourne
Links toward previous steps (curation, corpus...)
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Le document en format XML
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University of Queensland, Brisbane, QLD, Australia; Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Queensland, Brisbane, QLD, Australia; Royal Brisbane and Women's Hospital, Brisbane, QLD</wicri:regionArea><wicri:noRegion>QLD</wicri:noRegion></affiliation></author><author><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Bailey, Michael" sort="Bailey, Michael" uniqKey="Bailey M" first="Michael" last="Bailey">Michael Bailey</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Cooper, D James" sort="Cooper, D James" uniqKey="Cooper D" first="D James" last="Cooper">D James Cooper</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Duranteau, Jacques" sort="Duranteau, Jacques" uniqKey="Duranteau J" first="Jacques" last="Duranteau">Jacques Duranteau</name><affiliation wicri:level="3"><nlm:affiliation>Département d'Anesthésie-Réanimation, Hôpital de Bicêtre, Assistance Publique des Hopitaux de Paris, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département d'Anesthésie-Réanimation, Hôpital de Bicêtre, Assistance Publique des Hopitaux de Paris, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name><affiliation wicri:level="3"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Anaesthesiology and Intensive Care Medicine, CHU La Cavale Blanche, Brest, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Anaesthesiology and Intensive Care Medicine, CHU La Cavale Blanche, Brest</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Brest</settlement></placeName></affiliation></author><author><name sortKey="Mak, Anne" sort="Mak, Anne" uniqKey="Mak A" first="Anne" last="Mak">Anne Mak</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Mcarthur, Colin" sort="Mcarthur, Colin" uniqKey="Mcarthur C" first="Colin" last="Mcarthur">Colin Mcarthur</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Auckland City Hospital, Auckland, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Auckland City Hospital, Auckland</wicri:regionArea><wicri:noRegion>Auckland</wicri:noRegion></affiliation></author><author><name sortKey="Pettil, Ville" sort="Pettil, Ville" uniqKey="Pettil V" first="Ville" last="Pettil">Ville Pettil</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Helsinki and Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Skrifvars, Markus" sort="Skrifvars, Markus" uniqKey="Skrifvars M" first="Markus" last="Skrifvars">Markus Skrifvars</name><affiliation wicri:level="1"><nlm:affiliation>University of Helsinki and Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Vallance, Shirley" sort="Vallance, Shirley" uniqKey="Vallance S" first="Shirley" last="Vallance">Shirley Vallance</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Varma, Dinesh" sort="Varma, Dinesh" uniqKey="Varma D" first="Dinesh" last="Varma">Dinesh Varma</name><affiliation wicri:level="1"><nlm:affiliation>The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Wills, Judy" sort="Wills, Judy" uniqKey="Wills J" first="Judy" last="Wills">Judy Wills</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Melbourne, Melbourne, VIC, Australia; Austin Hospital, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; 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The Alfred, Melbourne, VIC, Australia; School of Medicine and Medical Sciences, University College Dublin, Dublin Ireland; St Vincent's University Hospital, Dublin, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia; School of Medicine and Medical Sciences, University College Dublin, Dublin Ireland; St Vincent's University Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="French, Craig" sort="French, Craig" uniqKey="French C" first="Craig" last="French">Craig French</name><affiliation wicri:level="4"><nlm:affiliation>University of Melbourne, Melbourne, VIC, Australia; Western Health, Melbourne, VIC, Australia. Electronic address: craig.french@wh.org.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Melbourne, Melbourne, VIC, Australia; Western Health, Melbourne, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Little, Lorraine" sort="Little, Lorraine" uniqKey="Little L" first="Lorraine" last="Little">Lorraine Little</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Haddad, Samir" sort="Haddad, Samir" uniqKey="Haddad S" first="Samir" last="Haddad">Samir Haddad</name><affiliation wicri:level="1"><nlm:affiliation>King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>King Abdulaziz Medical City, National Guard Health Affairs, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Presneill, Jeffrey" sort="Presneill, Jeffrey" uniqKey="Presneill J" first="Jeffrey" last="Presneill">Jeffrey Presneill</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Queensland, Brisbane, QLD, Australia; Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Queensland, Brisbane, QLD, Australia; Royal Brisbane and Women's Hospital, Brisbane, QLD</wicri:regionArea><wicri:noRegion>QLD</wicri:noRegion></affiliation></author><author><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Bailey, Michael" sort="Bailey, Michael" uniqKey="Bailey M" first="Michael" last="Bailey">Michael Bailey</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Cooper, D James" sort="Cooper, D James" uniqKey="Cooper D" first="D James" last="Cooper">D James Cooper</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Duranteau, Jacques" sort="Duranteau, Jacques" uniqKey="Duranteau J" first="Jacques" last="Duranteau">Jacques Duranteau</name><affiliation wicri:level="3"><nlm:affiliation>Département d'Anesthésie-Réanimation, Hôpital de Bicêtre, Assistance Publique des Hopitaux de Paris, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département d'Anesthésie-Réanimation, Hôpital de Bicêtre, Assistance Publique des Hopitaux de Paris, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name><affiliation wicri:level="3"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Anaesthesiology and Intensive Care Medicine, CHU La Cavale Blanche, Brest, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Anaesthesiology and Intensive Care Medicine, CHU La Cavale Blanche, Brest</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Brest</settlement></placeName></affiliation></author><author><name sortKey="Mak, Anne" sort="Mak, Anne" uniqKey="Mak A" first="Anne" last="Mak">Anne Mak</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Mcarthur, Colin" sort="Mcarthur, Colin" uniqKey="Mcarthur C" first="Colin" last="Mcarthur">Colin Mcarthur</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Auckland City Hospital, Auckland, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Auckland City Hospital, Auckland</wicri:regionArea><wicri:noRegion>Auckland</wicri:noRegion></affiliation></author><author><name sortKey="Pettil, Ville" sort="Pettil, Ville" uniqKey="Pettil V" first="Ville" last="Pettil">Ville Pettil</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Helsinki and Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Skrifvars, Markus" sort="Skrifvars, Markus" uniqKey="Skrifvars M" first="Markus" last="Skrifvars">Markus Skrifvars</name><affiliation wicri:level="1"><nlm:affiliation>University of Helsinki and Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Vallance, Shirley" sort="Vallance, Shirley" uniqKey="Vallance S" first="Shirley" last="Vallance">Shirley Vallance</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Varma, Dinesh" sort="Varma, Dinesh" uniqKey="Varma D" first="Dinesh" last="Varma">Dinesh Varma</name><affiliation wicri:level="1"><nlm:affiliation>The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Wills, Judy" sort="Wills, Judy" uniqKey="Wills J" first="Judy" last="Wills">Judy Wills</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; The Alfred, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><affiliation wicri:level="1"><nlm:affiliation>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Melbourne, Melbourne, VIC, Australia; Austin Hospital, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; University of Melbourne, Melbourne, VIC, Australia; Austin Hospital, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author></analytic><series><title level="j">Lancet (London, England)</title><idno type="eISSN">1474-547X</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Australia (epidemiology)</term><term>Brain Injuries (drug therapy)</term><term>Brain Injuries (mortality)</term><term>Double-Blind Method</term><term>Erythropoietin (therapeutic use)</term><term>Europe (epidemiology)</term><term>Female</term><term>Glasgow Outcome Scale</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>New Zealand (epidemiology)</term><term>Saudi Arabia (epidemiology)</term><term>Treatment Outcome</term><term>Venous Thrombosis (epidemiology)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Arabie saoudite (épidémiologie)</term><term>Australie (épidémiologie)</term><term>Europe (épidémiologie)</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Jeune adulte</term><term>Lésions encéphaliques (mortalité)</term><term>Lésions encéphaliques (traitement médicamenteux)</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Nouvelle-Zélande (épidémiologie)</term><term>Résultat thérapeutique</term><term>Thrombose veineuse (épidémiologie)</term><term>Échelle de suivi de Glasgow</term><term>Érythropoïétine (usage thérapeutique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Erythropoietin</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Australia</term><term>Europe</term><term>New Zealand</term><term>Saudi Arabia</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Brain Injuries</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Venous Thrombosis</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Brain Injuries</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Lésions encéphaliques</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lésions encéphaliques</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Érythropoïétine</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Arabie saoudite</term><term>Australie</term><term>Europe</term><term>Nouvelle-Zélande</term><term>Thrombose veineuse</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Double-Blind Method</term><term>Female</term><term>Glasgow Outcome Scale</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Jeune adulte</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Résultat thérapeutique</term><term>Échelle de suivi de Glasgow</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Australie</term><term>Nouvelle-Zélande</term><term>Arabie saoudite</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Erythropoietin might have neurocytoprotective effects. In this trial, we studied its effect on neurological recovery, mortality, and venous thrombotic events in patients with traumatic brain injury.</div></front></TEI><affiliations><list><country><li>Arabie saoudite</li><li>Australie</li><li>Finlande</li><li>France</li><li>Irlande (pays)</li><li>Nouvelle-Zélande</li></country><region><li>Région Bretagne</li><li>Victoria (État)</li><li>Île-de-France</li></region><settlement><li>Brest</li><li>Melbourne</li><li>Paris</li></settlement><orgName><li>Université de Melbourne</li></orgName></list><tree><country name="Irlande (pays)"><noRegion><name sortKey="Nichol, Alistair" sort="Nichol, Alistair" uniqKey="Nichol A" first="Alistair" last="Nichol">Alistair Nichol</name></noRegion></country><country name="Australie"><region name="Victoria (État)"><name sortKey="French, Craig" sort="French, Craig" uniqKey="French C" first="Craig" last="French">Craig French</name></region><name sortKey="Bailey, Michael" sort="Bailey, Michael" uniqKey="Bailey M" first="Michael" last="Bailey">Michael Bailey</name><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><name sortKey="Cooper, D James" sort="Cooper, D James" uniqKey="Cooper D" first="D James" last="Cooper">D James Cooper</name><name sortKey="Little, Lorraine" sort="Little, Lorraine" uniqKey="Little L" first="Lorraine" last="Little">Lorraine Little</name><name sortKey="Mak, Anne" sort="Mak, Anne" uniqKey="Mak A" first="Anne" last="Mak">Anne Mak</name><name sortKey="Presneill, Jeffrey" sort="Presneill, Jeffrey" uniqKey="Presneill J" first="Jeffrey" last="Presneill">Jeffrey Presneill</name><name sortKey="Vallance, Shirley" sort="Vallance, Shirley" uniqKey="Vallance S" first="Shirley" last="Vallance">Shirley Vallance</name><name sortKey="Varma, Dinesh" sort="Varma, Dinesh" uniqKey="Varma D" first="Dinesh" last="Varma">Dinesh Varma</name><name sortKey="Wills, Judy" sort="Wills, Judy" uniqKey="Wills J" first="Judy" last="Wills">Judy Wills</name></country><country name="Arabie saoudite"><noRegion><name sortKey="Haddad, Samir" sort="Haddad, Samir" uniqKey="Haddad S" first="Samir" last="Haddad">Samir Haddad</name></noRegion><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name></country><country name="France"><region name="Île-de-France"><name sortKey="Duranteau, Jacques" sort="Duranteau, Jacques" uniqKey="Duranteau J" first="Jacques" last="Duranteau">Jacques Duranteau</name></region><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Mcarthur, Colin" sort="Mcarthur, Colin" uniqKey="Mcarthur C" first="Colin" last="Mcarthur">Colin Mcarthur</name></noRegion></country><country name="Finlande"><noRegion><name sortKey="Pettil, Ville" sort="Pettil, Ville" uniqKey="Pettil V" first="Ville" last="Pettil">Ville Pettil</name></noRegion><name sortKey="Skrifvars, Markus" sort="Skrifvars, Markus" uniqKey="Skrifvars M" first="Markus" last="Skrifvars">Markus Skrifvars</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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